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AHR — IL2

Text-mined interactions from Literome

Jeon et al., J Immunol 2000 : We had previously shown that activation of the arylhydrocarbon receptor (AHR) , a member of the bHLH-PAS family of transcription factors, leads to increased mRNA expression of IL-2 in murine fetal thymocytes ... The IL-2 gene can be induced by the AHR also in thymocytes in vivo after injection of 2,3,7, 8-tetrachlorodibenzo-p-dioxin, a potent ligand of the AHR ... The AHR mediates the IL-2 induction as shown with AHR-deficient mice
Ishikawa et al., Int Immunol 2006 (Asthma...) : Thus, we examined the capacity of IL-2 and IL-18 to induce AHR , airway eosinophilic inflammation and goblet cell metaplasia