Gene interactions and pathways from curated databases and text-mining

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BCL3 — IGF1

Text-mined interactions from Literome

Fornoni et al., Am J Pathol 2001 : We investigated whether Bcl-xL and Fas/Fas-ligand were regulated by CsA in cultured podocytes and whether CsA induced apoptosis was prevented by HGF or IGF-I ... HGF, but not IGF-I , prevented apoptosis and restored Bcl-xL levels
Yamamura et al., Am J Physiol Heart Circ Physiol 2001 (Myocardial Reperfusion Injury) : IGF-I differentially regulates Bcl-xL and Bax and confers myocardial protection in the rat heart ... These results suggest that IGF-1 differentially regulates Bcl-xL and Bax in heart mitochondria, which may be causally related to myocardial protection against ischemia-reperfusion injury
Nakao et al., J Thorac Cardiovasc Surg 2001 (Disease Models, Animal...) : Immunohistochemical studies revealed that insulin-like growth factor 1 increased expression of the antiapoptotic Bcl-xL protein and inhibited expression of the proapoptotic Bax protein in motor neuron cells 24 and 48 hours after the operation
Brenne et al., Eur J Haematol 2009 (Multiple Myeloma) : Bcl-3 was induced in myeloma cell lines by interleukin (IL)-6, IL-21, IL-15, tumor necrosis factor-alpha and IGF-1 , and its upregulation was associated with increased proliferation of the cells
Singleton et al., J Biol Chem 1996 : Finally, increased neuronal IGF-IR expression enhances the negative death regulator Bcl-xL
Suzuki et al., FEBS Lett 1998 : It was also found that R-Ras and IGF-1 cooperatively induced Bcl-xL expression and inhibited caspase-3 activation