Gene interactions and pathways from curated databases and text-mining

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JUN — LTA

Text-mined interactions from Literome

Matsuguchi et al., Clin Diagn Lab Immunol 2003 : Lactobacillus LTA induced activation of c-Jun N-terminal kinase activation in RAW264.7 cells
Finney et al., Intensive Care Med 2012 : LPS and LTA activated NF-?B and AP-1 in J774 cells
Huang et al., Toxicol Appl Pharmacol 2013 (Inflammation) : Furthermore, stimulation of cells with LTA also activated I?Ba phosphorylation, p65 phosphorylation at Ser ( 536 ), and c-Jun phosphorylation ... Moreover, LTA induced increases of ?B-DNA and AP-1-DNA binding activity were inhibited by p38, JNK, and PI3-kinase inhibitors
Park et al., Int Immunopharmacol 2013 : Moreover, schizandrin C suppressed LTA induced nuclear factor-kappa B ( NF-?B ), activator protein-1 (AP-1) , janus-kinase/signal transducer and activator of transcription ( JAK-STATs ), and mitogen activated protein kinase ( MAPK ) activation