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NPY4R — SMAD2
Text-mined interactions from Literome
Maeda et al., J Biol Chem 2006
:
Unexpectedly,
PP1 prevented
Smad2/3 activation by TGF-beta1, whereas SU6656 did not
Ungefroren et al., Curr Cancer Drug Targets 2011
:
Likewise, PP2 and
PP1 but not SU6656 effectively blocked TGF-ß1 induced activation of Smad2 and p38 MAPK and partially
suppressed Smad activation and transcriptional activity on TGF-ß/Smad-responsive reporters of a kinase-active TßRI mutant ectopically expressed in Panc1 cells ... Likewise, PP2 and
PP1 but not SU6656 effectively
blocked TGF-ß1 induced activation of
Smad2 and p38 MAPK and partially suppressed Smad activation and transcriptional activity on TGF-ß/Smad-responsive reporters of a kinase-active TßRI mutant ectopically expressed in Panc1 cells