Gene interactions and pathways from curated databases and text-mining

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ELF3 — RELA

Text-mined interactions from Literome

Greene et al., J Immunol 2000 (Sarcoidosis, Pulmonary) : Examination of transcription factor activation and IL-2 gene expression in Jurkat T cells revealed that sarcoid but not normal ELF activated AP1 and NF-kappaB , induced IL-2 gene transcription, and up-regulated IL-2 protein production
Rudders et al., J Biol Chem 2001 (Inflammation...) : This induction occurs within hours of stimulation and is mediated by NF-kappaB transactivation of the ESE-1 promoter
Grall et al., Arthritis Rheum 2003 (Arthritis, Rheumatoid...) : Transient transfection experiments and EMSAs showed that induction of ESE-1 gene expression by IL-1beta requires activation of NF-kappaB and binding of p50 and p65 family members to the NF-kappaB site in the ESE-1 promoter