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NCF1 — RELA
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
NCF1
—
RELA
(direct interaction, pull down)
Gu et al., J Biol Chem 2003*
-
IRef Biogrid Interaction:
NCF1
—
RELA
(physical association, affinity chromatography technology)
Gu et al., J Biol Chem 2003*
-
IRef Intact Interaction:
NCF1
—
RELA
(physical association, two hybrid pooling approach)
Gu et al., J Biol Chem 2003*
-
IRef Intact Interaction:
NCF1
—
RELA
(physical association, anti tag coimmunoprecipitation)
Gu et al., J Biol Chem 2003*
-
IRef Intact Interaction:
NCF1
—
RELA
(direct interaction, pull down)
Gu et al., J Biol Chem 2003*
-
IRef Intact Interaction:
NCF1
—
RELA
(colocalization, fluorescence microscopy)
Gu et al., J Biol Chem 2003*
Text-mined interactions from Literome
Gu et al., J Biol Chem 2003
:
Overexpression of
p47(phox) synergized with IL-1beta in the activation of an artificial kappaB-luciferase reporter and specifically
augmented IL-1beta induced
RelA transactivation activity ...
p47(phox) overexpression also greatly
increased IL-1beta stimulated
RelA phosphorylation, whereas it had no effect on I-kappaB degradation or on RelA nuclear translocation or kappaB binding
Sadikot et al., J Immunol 2004
(Pneumonia, Bacterial...) :
p47phox deficiency
impairs NF-kappa B activation and host defense in Pseudomonas pneumonia
Gauss et al., J Leukoc Biol 2007
:
Pharmacological inhibitors of
NF-kappaB activation
blocked TNF-alpha induced up-regulation of
NCF1 , NCF2, and CYBB message, which correlated with a reduction in expression of the corresponding oxidase proteins and decreased O2*- production
Luengo-Blanco et al., Blood 2008
(Ectodermal Dysplasia...) :
This work investigated the functional
role of
nuclear factor-kappaB (NF-kappaB) in respiratory burst activity and in expression of the human phagocyte nicotinamide adenine dinucleotide phosphate ( NADPH ) oxidase genes CYBB, CYBA,
NCF1 , and NCF2 ... This work investigated the functional
role of
nuclear factor-kappaB (NF-kappaB) in respiratory burst activity and in expression of the human phagocyte nicotinamide adenine dinucleotide phosphate ( NADPH ) oxidase genes CYBB, CYBA,
NCF1 , and NCF2 ... These studies show that
NF-kappaB is
necessary for CYBB and
NCF1 gene expression and activation of the phagocyte NADPH oxidase in this model system