Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Sutherland et al., J Bacteriol 2008 : Accumulation of mutant topoisomerase I cleavage complex can lead to SOS induction and cell death in Escherichia coli
Liu et al., J Bacteriol 2009 : Escherichia coli expressing SOS inducing mutant topoisomerase I was utilized to demonstrate that covalent protein-DNA complex accumulation results in oxidative damage
Liu et al., J Antimicrob Chemother 2011 : The role of topoisomerase I in the SOS response was confirmed with quantitative western blot analysis of RecA following trimethoprim treatment