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CXCL12 — PI3

Text-mined interactions from Literome

Kanda et al., J Biol Chem 2003 : SDF-1alpha activated PI3-kinase in IBE cells ... Taken together, SDF-1alpha induces compact cell-cell contact through PI3-kinase , resulting in tube formation of endothelial cells
Curnock et al., J Immunol 2003 : In this study Jurkat clones were established, stably expressing dominant negative constructs of class IA and class IB PI 3-kinases under the control of the tetracycline off inducible gene system, to determine the relative roles of these PI 3-kinases in SDF-1 signaling
Fernandis et al., Oncogene 2004 (Breast Neoplasms...) : CXCL12 induced the activation of PI 3-kinase , and increased its association with Cbl and SHP2
Lee et al., Mol Cancer Res 2004 (Breast Neoplasms...) : Stromal cell derived factor 1alpha ( SDF-1alpha ; CXCL12 ) stimulation of breast cancer cells resulted in phosphoinositide 3-kinase (PI-3K) activation, AKT phosphorylation, and activation of the FKHRL1 transcription factor
Gálvez et al., J Biol Chem 2005 : Investigation of the signaling pathways involved in chemokine induced MT1-MMP activity in ECs revealed that CCL2 and CXCL8 induced cortical actin polymerization and sustained activation of phosphatidylinositol 3-kinase (PI3K) and the small GTPase Rac
Li et al., Chin Med J (Engl) 2006 (Endometrial Neoplasms) : Growth and activation of PI-3K/PKB and Akt by stromal cell derived factor 1alpha in endometrial carcinoma cells with expression of suppressor endoprotein PTEN
Amin et al., Arthritis Rheum 2007 (Arthritis, Rheumatoid) : IL-18 induced SDF-1alpha/CXCL12 up-regulation was dependent on JNK, p38 MAPK, phosphatidylinositol 3-kinase (PI3K) , and NFkappaB
Sameermahmood et al., Invest Ophthalmol Vis Sci 2008 : In addition, curcumin significantly ( P < 0.001 ) decreased SDF-1alpha induced HRECs migration and downregulated SDF-1alpha induced expression of CXCR4, phospho-AKT, phospho-phosphatidylinositol-3-kinase (PI3-K) , and eNOS
Lin et al., J Biol Chem 2011 : In this study, we further investigated the roles of Rac1, phosphoinositide 3-kinase (PI3K) , and Akt in thrombin induced NF-?B activation and IL-8/CXCL8 expression
Wang et al., World J Gastroenterol 2011 (Colonic Neoplasms) : SDF-1 induced phosphorylation of phosphatidylinositol 3-kinase (PI3K)/AKT and ß-catenin was detected by Western blotting