Gene interactions and pathways from curated databases and text-mining

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HOXB13 — TCF4

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: TCF4 → HOXB13 (decreases, HOXB13 Activity) Jung et al., Cancer Res 2004*
    Evidence: Western blot analysis demonstrated that HOXB13 down-regulates the expression of TCF-4 and its responsive genes, c-myc and cyclin D1.HOXB13 specifically suppresses T-cell factor 4 transcriptional activity.

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *