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Ariumi et al., Oncogene 1999
:
Thus, DNA-PK suppresses PARP activity, probably through direct binding and/or sequestration of DNA-ends which serve as an important stimulator for both enzymes
Veuger et al., Oncogene 2004
:
The inhibitory effect of DNA-PK on PARP activity was confirmed in permeabilized cells
Dregalla et al., Aging 2010
(Chromosomal Instability...) :
We provide the first evidence for regulation of DNA-PKcs by tankyrase 1 PARP activity and taken together, identify roles of tankyrase 1 with implications not only for DNA repair and telomere biology, but also for cancer and aging
Ruscetti et al., J Biol Chem 1998
:
The protein kinase activity of DNA-PK can be stimulated by PARP in the presence of NAD+ in a reaction that is blocked by the PARP inhibitor 1, 5-dihydroxyisoquinoline