◀ Back to IFNG

IFNG — SOD2

Text-mined interactions from Literome

Maehara et al., FEBS Lett 1999 : Cooperative interaction of NF-kappaB and C/EBP binding sites is necessary for manganese superoxide dismutase gene transcription mediated by lipopolysaccharide and interferon-gamma ... This report provides the first evidence that cooperation between two distinct cis acting elements may be required for induction of Mn-SOD gene expression mediated by lipopolysaccharide and interferon-gamma
Strålin et al., Atherosclerosis 2000 : The Mn-SOD activity was strongly up-regulated by TNF-alpha and IL-1alpha and moderately by IFN-gamma
Piganelli et al., Diabetes 2002 (Diabetes Mellitus, Experimental...) : We found that the SOD mimic significantly inhibited antigen presenting cell dependent T-cell proliferation and IFN-gamma production in vitro
Ono et al., Biochem Biophys Res Commun 1992 (Carcinoma, Hepatocellular...) : Effects of Tumor Necrosis Factor (TNF), Interleukin-1 (IL-1), Interleukin-6 (IL-6) and Interferon-gamma (IFN-gamma) on the expression of Mn-superoxide dismutase ( Mn-SOD ) protein were investigated in human hepatoma cells, Hu-H1, which revealed resistance to the cytotoxicity of TNF and IL-1
Marklund et al., J Biol Chem 1992 : TNF-alpha, IL-1 alpha, and IFN-gamma stimulated the Mn-SOD activity, as previously known, and these responses were reduced by TGF-beta
Bian et al., Zhonghua Nan Ke Xue 2007 : TNF-alpha showed stronger inhibiting effect, IFN-gamma markedly reduced the activities of Na+ -K+ -ATPase, Ca2+ -ATPase and SOD in sperm ( P < 0.01 ), and their synergistic action was weaker
Harris et al., J Immunol 1991 : Manganese superoxide dismutase is induced by IFN-gamma in multiple cell types ... Mn-SOD is induced by IFN-gamma and also by TNF in all four human cell lines examined : HS153 fibroblasts, ACHN renal carcinoma, A549 lung carcinoma, and A375 melanoma ... The induction of Mn-SOD by IFN-gamma and its synergistic induction by IFN-gamma in combination with TNF and IL-1 should protect healthy cells from the toxicity of O2- during an immune response, and may provide a mechanism for selective killing of infected cells
Stefanova et al., Z Naturforsch C 2010 (Arthritis, Experimental...) : Yeast SOD treatment effectively suppressed the spontaneous and recombinant mouse IFN-gamma + LPS induced release of NO as well
Dobashi et al., J Neurochem 1997 : In spite of the stimulation of mRNA level, LPS and IFN-gamma significantly inhibited the activity of Mn-SOD within the first 24 h of incubation ; however, Mn-SOD activity gradually increased with the increase in time of incubation
Sano et al., Immunology 1997 : IFN-gamma induces expression of inducible NO synthase (iNOS), manganese superoxide dismutase ( Mn-SOD ) and copper zinc SOD ( CuZn-SOD ) in these cells
Takahashi et al., J Dermatol Sci 1998 : Interferon-gamma dependent induction of manganese superoxide dismutase activity of SV40 transformed human keratinocytes by anti-Fas antibody and by TNF-alpha ... The induction of IFN-gamma dependent Mn-SOD activity by anti-Fas antibody or TNF-alpha was concentration dependent ; the maximal effect was observed at 1-10 micrograms/ml and 5-10 ng/ml, respectively ... Although the addition of 12-o-tetradecanoylphorbol-13-acetate ( TPA ) singly to the incubation medium had no effect on either Mn-, or Cu, Zn-SOD activity, it significantly augmented the IFN-gamma dependent induction of Mn-SOD activity by anti-Fas antibody or by TNF-alpha ... These results indicate that the stimulation of Fas antigen or TNF receptor increases Mn-SOD activity of SVHK cells in the presence of IFN-gamma and that TPA augments the process through the activation of protein kinase C
Habelhah et al., Hokkaido Igaku Zasshi 1998 (Disease Progression...) : In vitro experiments proved that although IFN-gamma did not increase the production of Mn-SOD by itself, concomitant treatment with both IFN-gamma and TNF-alpha enhanced the Mn-SOD production in QR-32 cells greatly