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RNF19A — TYR
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Suzuki et al., J Cell Biochem 2012
:
Pharmacological experiments showed that
p38 mitogen activated protein kinase ( MAPK ) was involved in the signaling pathways mediating the spreading dependent activation of NADPH oxidase, and that its spreading dependent phosphorylation of Thr-180 and
Tyr-182 , a hallmark of activation, was
impaired at acidic pH
Zhou et al., J Ethnopharmacol 2012
(Melanoma, Experimental) :
The special
p38 MAPK inhibitor, SB203580, and protein kinase A (PKA) inhibitor, H89, both
attenuated the AVE induced up-regulation of MITF and
tyrosinase expression in B16F10 cells and NHMC