UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

NCI Pathway Database Validated targets of C-MYC transcriptional repression: IRF-8 (IRF8) → MYC/Max/MIZ-1 complex (MYC-MAX-ZBTB17) (modification, collaborate)
Alter-Koltunoff et al., J Biol Chem 2008, Peukert et al., EMBO J 1997, Salghetti et al., EMBO J 1999
Evidence: mutant phenotype, physical interaction
NCI Pathway Database Validated targets of C-MYC transcriptional repression: IRF-8 (IRF8) → MYC/Max complex (MYC-MAX) (modification, collaborate) Alter-Koltunoff et al., J Biol Chem 2008, Peukert et al., EMBO J 1997, Salghetti et al., EMBO J 1999
Evidence: mutant phenotype, physical interaction
NCI Pathway Database Validated targets of C-MYC transcriptional repression: MIZ-1/IRF8 complex (ZBTB17-IRF8) → MYC/Max/MIZ-1 complex (MYC-MAX-ZBTB17) (modification, collaborate)
Alter-Koltunoff et al., J Biol Chem 2008, Peukert et al., EMBO J 1997, Salghetti et al., EMBO J 1999
Evidence: mutant phenotype, physical interaction
NCI Pathway Database Validated targets of C-MYC transcriptional repression: MIZ-1/IRF8 complex (ZBTB17-IRF8) → MYC/Max complex (MYC-MAX) (modification, collaborate) Alter-Koltunoff et al., J Biol Chem 2008, Peukert et al., EMBO J 1997, Salghetti et al., EMBO J 1999
Evidence: mutant phenotype, physical interaction