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PLD1 — SYK

Pathways - manually collected, often from reviews:

• KEGG Fc gamma R-mediated phagocytosis: SYK → PLD1/PLD2 (protein-protein, activation)

Text-mined interactions from Literome

Hitomi et al., FEBS Lett 1999 : Cross linking of the B cell receptor induces activation of phospholipase D through Syk , Btk and phospholipase C-gamma2 ... These results demonstrate that Syk , Btk and PLC-gamma2 are essential for BCR induced PLD activation
Hitomi et al., Blood 2004 : However, FcepsilonRI induced PLD activation required Syk and was downstream of the Ca ( 2+ ) response, suggesting that basal PLD1 activity rather than that activated by cell stimulation controlled these early signaling events