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IFNG — TFRC
Text-mined interactions from Literome
Ryu et al., Anticancer Res 2000
:
While all tested cytokines individually and in combination inhibited the expression of the transferrin receptor (TfR) on macrophages,
IFN gamma alone and in combination with other cytokines most strongly
repressed the
TfR expression
Bourgeade et al., Nucleic Acids Res 1992
:
IFN gamma inhibits the rise in
transferrin receptor mRNA level which is normally observed when stationary WISH cells are stimulated to proliferate
Tacchini et al., J Biol Chem 2008
(Inflammation) :
Activation of an anti-inflammatory pathway by pre-exposure to the adenosine A(2A) receptor agonist CGS21680 prevented the inducing
effect of
LPS/IFNgamma on HIF-1 and
TfR1 expression by inhibiting NF-kappaB activity, whereas treatment with CGS21680 alone increased HIF-1 mediated TfR1 expression by means of an NF-kappaB independent signaling pathway
Myers et al., J Immunol 1989
:
In contrast, the expression of
transferrin receptor mRNA transcripts, which were also constitutively expressed throughout the entire culture period, were not affected by
stimulation with either endotoxin or
IFN-gamma
Ramanathan et al., J Biol Chem 1994
:
The activity of oligo I in the HeLa S3 cell line inhibits the
interferon-gamma mediated enhancement of both ICAM-1 and MHC Class II DR and the interferon-gamma mediated reduction in
transferrin receptor expression
Iwagaki et al., Res Commun Mol Pathol Pharmacol 1994
(Leukemia, Myelogenous, Chronic, BCR-ABL Positive) :
These results suggested that the early phase of upregulation of
Tf-R induced by
IFN-gamma was caused by increased CMF, and the late phase of upregulation of Tf-R was due to increased rigidity of CMF