Gene interactions and pathways from curated databases and text-mining

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SLC22A3 — ZYX

Text-mined interactions from Literome

Mori et al., Mol Biol Cell 2009 : Thus, zyxin reorganizes actin fibers and enhances cell motility in response to TGF-beta1, thereby regulating EMT
Mise et al., J Biol Chem 2012 (Lung Neoplasms) : Zyxin concentrates at focal adhesions and along the actin cytoskeleton ; as such, we hypothesized that cytoskeletal organization, motility, and EMT in response to TGF-ß1 might be regulated by zyxin expression ... By regulating cell-cell junctions, integrin a5ß1 expression, and cell-extracellular matrix adhesion, zyxin may regulate cancer cell motility and EMT during lung cancer development and progression