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AKT2 — SFTPC

Text-mined interactions from Literome

Afrasiabi et al., Mol Cell Endocrinol 2007 (Thyroid Neoplasms) : SPC reduced the phosphorylation of Akt with about 50 % and evoked a substantial decrease in the amount of phosphorylated mitogen activated protein ( MAP ) kinase ... Taken together, SPC is an effective suppressor of thyroid cancer cell proliferation and migration, and this effect is, in part, mediated by inhibition of both the PI3K-Akt and the MAP kinase signalling pathways
Jeong et al., J Biomed Sci 2011 (Hypopigmentation) : It was found that SPC induced not only activation of Akt but also stimulation of mTOR, a downstream mediator of the Akt signaling pathway