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JAK1 — KLK3

Text-mined interactions from Literome

Wakioka et al., Leukemia 1999 : Therefore, one of the major functions of APS is in recruitment of c-Cbl into the receptor/JAK complex, thereby inhibiting JAK signaling activity
O'Brien et al., J Biol Chem 2002 : These results suggest that 1 ) SH2-B beta specifically activates JAK2, 2 ) APS negatively regulates both JAK2 and JAK1 , and 3 ) both SH2-B beta and APS may serve as adapter proteins for all three JAKs independent of any role they have in JAK activity