Zhu et al., J Biol Chem 2009
:
Although pro-inflammatory cytokine and Ig production induced by CpG require TLR9 expression, we also found that SR-B1 negatively regulates TLR9 dependent production of interleukin-6, interleukin-10 , and IgM
Feng et al., Arterioscler Thromb Vasc Biol 2011
(Autoimmune Diseases...) :
Further analyses revealed that SR-BI deficiency enhanced lymphocyte proliferation, caused imbalanced interferon-? and interleukin-4 production in lymphocytes, and caused elevated inflammatory cytokine production in macrophages