Gene interactions and pathways from curated databases and text-mining

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CALM3 — ITPR2

Pathways - manually collected, often from reviews:

  • KEGG Oocyte meiosis: ITPR1/ITPR2/ITPR3 → CALM1/CALM2/CALM3/CALML3/CALML5/CALML6 (enzyme-enzyme, compound)
  • KEGG Long-term potentiation: CALM1/CALM2/CALM3/CALML3/CALML5/CALML6 → ITPR1/ITPR2/ITPR3 (protein-protein, compound)
  • KEGG GnRH signaling pathway: ITPR1/ITPR2/ITPR3 → CALM1/CALM2/CALM3/CALML3/CALML5/CALML6 (protein-protein, compound)

Text-mined interactions from Literome

Kasri et al., Biol Res 2004 : Here we focus on the mechanism by which CaM regulates the inositol 1,4,5-trisphosphate receptor ( IP3R )
Miyakawa et al., BMC nephrology 2013 (Calcium Signaling) : Intracellular Ca2+ buffering with BAPTA, inositol 1,4,5-trisphosphate receptor ( InsP3R ) inhibition with 2-aminoethoxydiphenyl borate ( 2-APB ) or Ca2+/Calmodulin dependent kinase inhibition with KN-93 completely abolished ouabain stimulated PC2 translocation to the PM