Chong et al., J Immunol 2004
(Diabetes Mellitus, Type 1...) :
Fas expression was up-regulated on beta cells in vivo in prediabetic NOD8.3 mice, and this was inhibited by SOCS-1 Angstetra et al., Immunol Cell Biol 2009
(Diabetes Mellitus, Type 1...) :
SOCS1 overexpression prevented Fas upregulation on NOD4.1 beta-cells, but did not prevent islet destruction because SOCS1 transgenic islets were killed when grafted into NOD4.1.scid mice