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IRF6 — PLG
Text-mined interactions from Literome
Mochizuki et al., J Periodontal Res 1999
:
Enhancement of
LPS stimulated
plasminogen activator production in aged gingival fibroblasts
Xiao et al., J Periodontal Res 2001
:
These results indicate that
LPS derived from periodontal pathogens may
cause unbalanced regulation of
plasminogen activator and plasminogen activator inhibitor by HGF and such an effect may, in part, contribute to the destruction of periodontal connective tissue through dysregulated pericellular proteolysis
Vairo et al., J Cell Physiol 1992
:
TNF alpha and
LPS inhibited both CSF-1 stimulated urokinase-type
plasminogen activator ( u-PA ) mRNA levels and u-PA activity in BMM, whereas IFN gamma lowered only the u-PA activity
Liu et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2005
:
To determine the effect of indomethacin on high concentration glucose and
lipopolysaccharide (LPS) induced fibronectin ( FN ) and
plasminogen activator inhibitor-1 ( PAI-1 ) secretion in cultured human peritoneal mesothelial cells
Bergheim et al., J Pharmacol Exp Ther 2006
(Inflammation) :
Furthermore,
PH/LPS caused a > 200x increase in hepatic
plasminogen activator inhibitor 1 ( PAI-1 ) mRNA expression and plasma PAI-1 protein
Radwan et al., Proteomics 2008
:
In contrast,
LPS induced expression of
plasminogen activator 2 protein but not mRNA is strongly enhanced in the absence of Tyk2
Drapier et al., Int J Immunopharmacol 1984
(Inflammation) :
Involvement of prostaglandins in
LPS mediated regulation of
plasminogen activator synthesis by inflammatory macrophages
Ogura et al., J Periodontal Res 1995
(Gingivitis) :
The C. rectus
LPS stimulated the
plasmin activity in the conditioned medium of Gin-1 cells in a time- and dose dependent manner, and C. rectus LPS also stimulated the PA activity in the conditioned medium
Eggesbø et al., Thromb Res 1995
(Hyperlipoproteinemias...) :
LPS induced procoagulant activity and
plasminogen activator activity in mononuclear cells from persons with high or low levels of HDL lipoprotein
Fearns et al., Am J Pathol 1997
:
We previously demonstrated that
lipopolysaccharide (LPS) induces
plasminogen activator inhibitor 1 ( PAI-1 ) gene expression primarily in endothelial cells in most organs of the mouse, with maximal induction by 3 hours