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ATP5O — SRC

Text-mined interactions from Literome

Ferrandi et al., J Biol Chem 2004 (Hypertrophy) : The high affinity site for ouabain is associated with Src dependent tyrosine phosphorylation of rat alpha1 Na-K ATPase
Tian et al., Mol Biol Cell 2006 : Functionally, binding of Src to either the Na+/K+-ATPase or GST-CD3 inhibited Src activity
Tian et al., J Biol Chem 2009 : Mechanistically, both Src and caveolin-1 are required for ouabain induced activation of Akt and up-regulation of Na/K-ATPase
Li et al., J Biol Chem 2009 (Hypertrophy) : We have previously shown that the Na/K-ATPase binds and inhibits Src ... Here, we report the molecular mechanism of Na/K-ATPase mediated Src regulation and the generation of a novel peptide Src inhibitor that targets the Na/K-ATPase/Src receptor complex and antagonizes ouabain induced protein kinase cascades
Lei et al., Am J Physiol Lung Cell Mol Physiol 2011 : In summary, in adult rat AECs T3-stimulated Src kinase activity can activate both PI3K/Akt and MAPK/ERK1/2, and activation of Akt is necessary for T3-induced Na-K-ATPase activity
Ye et al., J Biol Chem 2013 : Using purified enzyme we found that the a1 Na/K-ATPase might interact with and regulate Src activity in a conformation dependent manner