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F2RL1 — PI3

Text-mined interactions from Literome

Tanaka et al., Biochem Biophys Res Commun 2008 : The PAR2 triggered IL-8 release was suppressed by inhibitors of MEK ( U0126 ) or PI3-kinase ( LY294002 ), and PAR2 stimulation indeed activated the downstream kinases, ERK and Akt
Saito et al., Hum Reprod 2011 (Endometriosis...) : To study intracellular signaling, effects of inhibitors of mitogen activated protein kinases ( MAPKs ) and phosphoinositide 3-kinase (PI3K) and of Smad4 siRNA on the TGF-ß1 induced PAR2 gene expression were studied