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EPHB2 — FCGR3B
Text-mined interactions from Literome
Hazan-Halevy et al., J Biol Chem 2000
:
Cross linking of FcgammaRIIA or
FcgammaRIIIB induces p38 mitogen activated protein ( MAP ) kinase and
extracellular regulated kinase (ERK) phosphorylation
Coxon et al., J Immunol 2000
:
Homotypic and heterotypic cross linking of Fc gamma RIIa and/or
Fc gamma RIIIb resulted in a rapid, transient increase in
ERK and p38 activity, with maximal stimulation between 1 and 3 min. Fc gamma RIIa and Fc gamma RIIIb stimulated distinct patterns of ERK and p38 activity, and heterotypic cross linking failed to stimulate synergistic activation of either ERK or p38 activity ... Our data indicate that Fc gamma RIIa and
Fc gamma RIIIb independently
activate ERK and p38
García-García et al., J Immunol 2009
:
FcgammaRIIIB , but not FcgammaRIIA,
promoted a robust increase in phosphorylated
ERK in the nucleus, and also efficient phosphorylation of the NF Elk-1 ...
FcgammaRIIIB induced nuclear phosphorylation of
ERK , and of Elk-1, was not affected by Syk, PI3K, or MEK inhibitors ... Also,
ERK , but not MEK, was constitutively present in the nucleus, and
FcgammaRIIIB cross linking did not
increase the levels of nuclear ERK or MEK