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OLR1 — TNF

Text-mined interactions from Literome

Chiba et al., Biochem Biophys Res Commun 2001 (Arteriosclerosis) : PPARgamma ligands inhibit TNF-alpha induced LOX-1 expression in cultured endothelial cells ... Natural PPARgamma ligand 15-deoxy-Delta ( 12,14 ) -prostaglandin J ( 2 ) ( 15d-PGJ ( 2 ) ) and the thiazolidinediones, pioglitazone and troglitazone, decreased TNF-alpha induced LOX-1 mRNA expression in BAEC ... In contrast, PPARalpha ligands, Wy14643 and fenofibric acid, did not alter TNF-alpha induced LOX-1 expression ... Taken together, PPARgamma activators inhibit TNF-alpha induced LOX-1 expression in cultured BAEC, which may beneficially influence inflammatory responses in atherosclerosis
Mehta et al., Arterioscler Thromb Vasc Biol 2003 : LOX-1 , a novel lectin-like receptor for oxidized LDL ( ox-LDL ), is expressed in response to ox-LDL, angiotensin II (Ang II), tumor necrosis factor (TNF)-alpha , and other stress stimuli
Shibata et al., Atherosclerosis 2007 : Mulberry leaf aqueous fractions inhibit TNF-alpha induced nuclear factor kappaB (NF-kappaB) activation and lectin-like oxidized LDL receptor-1 ( LOX-1 ) expression in vascular endothelial cells
Liang et al., Cancer Lett 2007 (Breast Neoplasms) : Up-regulation of LOX-1 expression by TNF-alpha promotes trans-endothelial migration of MDA-MB-231 breast cancer cells ... We showed that up-regulation of endothelial LOX-1 by TNF-alpha promoted the adhesion and trans-endothelial migration of MDA-MB-231 breast cancer cells
Rudijanto et al., Acta Med Indones 2007 (Arteriosclerosis...) : LOX-1 expression increased also through oxygen species ( ROS ), endothelin-1 (ET-1), tumor necrosis factor-alpha (TNF-alpha), shear stress, activation of protein kinase-C ( PKC ), angiotensin-II (ANG-II), and through inflammatory pathways
Zhang et al., Clin Sci (Lond) 2009 (Vascular Diseases) : AGEs ( advanced glycation end-products ) /RAGE ( receptor for AGEs ), LOX-1 [ lectin-like oxidized low-density lipoprotein receptor-1 ) and NF-kappaB ( nuclear factor kappaB ) signalling play key roles in TNF-alpha expression through an increase in circulating and/or local vascular TNF-alpha production
Lee et al., Biosci Biotechnol Biochem 2010 (Hypercholesterolemia) : Leonurus sibiricus herb extract suppresses oxidative stress and ameliorates hypercholesterolemia in C57BL/6 mice and TNF-alpha induced expression of adhesion molecules and lectin-like oxidized LDL receptor-1 in human umbilical vein endothelial cells
Chen et al., Am J Physiol Heart Circ Physiol 2010 (Atherosclerosis...) : Adiponectin reduced TNF-alpha induced LOX-1 expression
Kume et al., Circ Res 1998 : Nuclear runoff assay revealed that TNF-alpha stimulates transcription of the LOX-1 gene