Gene interactions and pathways from curated databases and text-mining

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ANPEP — IL10

Text-mined interactions from Literome

Huschak et al., Clin Exp Immunol 2003 (Craniocerebral Trauma...) : Because lipopolysaccharide (LPS) and the anti-inflammatory cytokine interleukin (IL)-10 have been shown to be involved in the depressed HLA-DR expression on monocytes in trauma patients, we studied the in vitro effects of LPS and interleukin (IL)-10 on the expression of CD13 on monocytes prepared from the peripheral blood of healthy volunteers
Kehlen et al., Cancer Res 2003 (Carcinoma...) : In the undifferentiated thyroid carcinoma cell line 1736, APN/CD13 mRNA expression could be increased by epidermal growth factor, basic fibroblast growth factor, interleukin-6 , and tumor necrosis factor alpha
Bank et al., Int Immunopharmacol 2006 (Body Weight...) : Based on the findings that DPIV and APN inhibitors induce the TGF-beta1 and IL-10 production and a suppression of T helper cell proliferation in parallel, and that particularly APN inhibitors amplify the suppressing activity of regulatory T cells, both peptidases represent a promising target complex for treatment of diseases associated with an imbalanced T cell response, such as inflammatory bowel diseases ( IBD )
Ponemone et al., Clinical and translational gastroenterology 2010 : Leptin and APN enhanced interleukin (IL)-10 production by anti-CD3 stimulated LPL-T in IBD only