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GATA3 — JUN
Pathways - manually collected, often from reviews:
Text-mined interactions from Literome
Zhang et al., Proc Natl Acad Sci U S A 1999
:
We demonstrate further that
GATA inhibits binding of PU.1 to
c-Jun , a critical coactivator of PU.1 transactivation of myeloid promoters
El Gazzar et al., Inflamm Res 2007
:
Chromatin immunoprecipitation revealed that GATA,
AP-1 and NF-AT binding to IL-5 promoter was induced by LPS stimulation and that TQ
inhibited GATA binding at the IL-5 promoter but did not affect AP-1 and NF-AT binding
Gong et al., Mol Cell Biol 1993
:
Thus,
GATA-1 regulates the response of the epsilon-globin gene to enhancers through a specific site in the promoter and
requires enhancer
AP-1/NF-E2 binding to transduce the enhancer effect on transcription