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CYR61 — TCF4

Text-mined interactions from Literome

Tong et al., Oncogene 2004 (Carcinoma, Non-Small-Cell Lung...) : In this pathway, Cyr61 activated the beta-catenin/TCF4 complex, which promoted the expression of c-myc and the latter induced expression of p53, and p53 upregulated p21WAF1 and p130/RB2, resulting in growth arrest
Lin et al., J Endod 2013 : In this study, the role of transcription factor Forkhead/winged helix box protein O3a ( FoxO3a ) in Cyr61 expression and its modulation by simvastatin were investigated in cultured murine osteoblasts and a rat model of induced apical periodontitis