Gene interactions and pathways from curated databases and text-mining

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PC — TNF

Text-mined interactions from Literome

Devos et al., Eur Cytokine Netw 2004 (Hypersensitivity) : PCB 153 reduced the levels of IL-10, IFN-gamma and TNF-alpha
Xie et al., Zhongguo Zhong Xi Yi Jie He Za Zhi 2009 (Reperfusion Injury) : As compared with the model group, the serum level of NO and TNF-alpha significantly reduced in all the PCB treated groups ( P < 0.01 or P < 0.05 )
De et al., Environ Int 2010 : Further in-silico analysis showed that PCB-153 most likely acted through the TNF receptor, leading to oxidative stress involving metallothionein gene families, and causing apoptosis mainly by the Fas receptor signaling pathway