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BMP6 — NOS2

Text-mined interactions from Literome

Hong et al., Immunology 2009 : In addition, BMP-6 induced expression of pro-inflammatory inducible nitric oxide synthase (iNOS) and the cytokine tumour necrosis factor (TNF)-alpha ... In addition, BMP-6 induced expression of pro-inflammatory inducible nitric oxide synthase (iNOS) and the cytokine tumour necrosis factor (TNF)-alpha
Kwon et al., Immunology 2009 : Bone morphogenetic protein-6 induces the expression of inducible nitric oxide synthase in macrophages ... Induction of iNOS was inhibited by both cycloheximide and actinomycin D, indicating that the induction of iNOS expression by BMP-6 requires new protein synthesis ... Mechanistic studies revealed that the BMP-6 induced iNOS expression requires both Smads and nuclear factor-kappa B (NF-kappaB) signalling pathways