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IRF6 — LITAF

Text-mined interactions from Literome

Tang et al., Proc Natl Acad Sci U S A 2005 : LPS induces the interaction of a transcription factor, LPS induced TNF-alpha factor , and STAT6 ( B ) with effects on multiple cytokines
Shiomi et al., FEMS Immunol Med Microbiol 2006 : These results suggest that the consensus sequence for HNF-3alpha, or a nuclear binding protein to the CTCCC motif, may play an important role in regulating LPS dependent LITAF transcription
Tang et al., Cancer Res 2007 : Transfection of p53pep164 into H1299 cells significantly down-regulated LPS induced LITAF expression as well
Kim et al., J Immunol 2008 (MAP Kinase Signaling System...) : It also inhibited the degradation of IkappaBalpha and IkappaBbeta, as well as the activation of the LPS induced TNF-alpha factor in response to subsequent LPS stimulation
Tang et al., J Innate Immun 2010 (Shock, Septic) : We recently identified a LITAF-STAT6 ( B ) complex regulated by p38 MAPK in response to LPS stimulation ... Here, we identified PTP4A3, a protein tyrosine phosphotase, as a novel negative regulator of LPS induced LITAF/TNF-alpha production ... Further structure-function analysis revealed that a unique short peptide ( PIMAP39 ) derived from PTP4A3 is capable of mimicking the functionality of full-length PTP4A3 to selectively dephosphorylate p38 alpha and indirectly suppress LPS induced LITAF-STAT6B complex when it is translocated from the cytoplasmic region to the nucleus of the cell
Bushell et al., PloS one 2011 (Inflammation) : LITAF mRNA and protein levels were elevated in LPM from TNBS compared with untreated animals and LPS further increased LITAF protein levels in LPM from inflamed tissue ( P < 0.05 )
Xu et al., PloS one 2012 : Anti-CaHMGB was added to the RLO/LPS challenged hemocyte monolayer and real-time RT-PCR showed that administration of anti-CaHMGB dramatically reduced the rate of RLO/LPS induced up-regulation of LITAF at 4-12 h after treatment