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EGF — SOS2

Text-mined interactions from Literome

Akamatsu et al., J Biol Chem 1999 : Phosphatase treatment of lysates restored the binding of Sos to vinexin, suggesting that signaling from serum, EGF , or PDGF regulates the vinexin-Sos complex through the Sos phosphorylation
Oh-hora et al., J Exp Med 2003 : The BCR requires RasGRP3 ; in contrast, epidermal growth factor receptor is dependent on Sos1 and Sos2
Zhao et al., Nat Cell Biol 2007 : This interaction is essential for epidermal growth factor (EGF) induced Sos membrane recruitment and Ras activation
Medema et al., Mol Cell Biol 1994 : Calcium treatment, however, did not interfere with EGF induced EGF receptor autophosphorylation or association of mammalian SOS with the EGF receptor and Shc
Basu et al., Oncogene 1994 : The binding of Sos to tyrosine phosphorylated receptor, via Grb2 may also contribute to Ras activation by EGF but not NGF, while stable complex formation between Shc and receptors is not necessary for Ras activation by either growth factor
Holt et al., J Biol Chem 1996 : Although EGF stimulation of the mutant EGF receptor activates ERK and phosphorylation of both Shc and SOS , it fails to directly associate with either Shc or Grb2
Douville et al., Oncogene 1997 : EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2
Ishiki et al., Endocrinology 1997 : Neither insulin nor EGF treatment induced Crk-II association with either Sos or C3G
Kavanagh et al., Radiat Res 1998 : In contrast, EGF activated SOS as shown by the enhanced association of SOS with EGFR in co-immunoprecipitation experiments