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BMP4 — SOX9
Text-mined interactions from Literome
Nonaka et al., Int J Dev Biol 1999
:
When BMP4- and EGF soaked beads were implanted in juxtaposition within embryonic day 10 mouse mandibular processes, the incidence and amount of ectopic cartilage, and
Sox9 and type II collagen expression
induced by
BMP4 , were significantly reduced as the concentration of EGF was increased
Zeng et al., Genes Dev 2002
:
We have found that in the
presence of
BMP signals,
Sox9 and Nkx3.2 induce each other 's expression
Theodosiou et al., Dev Biol 2005
:
Despite these similarities, our evidence suggests that
Sox9 and Nkx2.5 are
regulated independently by
BMP signaling, and act coordinately to specify the pyloric sphincter
Sakai et al., Development 2006
:
In this study, our gain-of-function and loss-of-function experiments reveal that
Sox9 is
essential for
BMP signal mediated induction of Snail2 and subsequent EMT in avian neural crest
Pan et al., J Cell Physiol 2008
:
In the MEFs,
BMP-2 efficiently
induced Sox9 expression along with chondrogenic differentiation in a time- and dose dependent manner
Wang et al., Gastroenterology 2010
(Adenocarcinoma...) :
BMP4 signaling
induces expression of
SOX9 , an intestinal crypt transcription factor, which is highly expressed in Barrett 's epithelium