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HRAS — LPA
Text-mined interactions from Literome
Nebesio et al., Glia 2007
(Disease Models, Animal...) :
Furthermore,
LPA induced a higher level of
Ras-GTP and Akt phosphorylation in Nf1-/- SCs as compared to WT cells
Luttrell et al., J Biol Chem 1995
:
The IGF1,
LPA , and EGF receptor mediated signals are all sensitive to inhibitors of tyrosine protein kinases,
require p21ras activation, and are independent of protein kinase C
van Corven et al., Proc Natl Acad Sci U S A 1993
:
Thus, a heterotrimeric G protein of the Gi subfamily regulates
activation of
p21ras by
LPA and thrombin, possibly through an intermediary tyrosine kinase
Hordijk et al., J Biol Chem 1994
:
Furthermore,
LPA rapidly
activates p21ras through a pertussis toxin-sensitive pathway