Fehmann et al., Endocrinology 1992
(Insulinoma...) :
We conclude that galanin inhibits GLP-I ( 7-37 ) -stimulated proinsulin gene expression by inhibiting the activation of adenylate cyclase by GLP-I ( 7-37 ) and subsequently the production of cAMP in B-cells
Hargrove et al., Regul Pept 2007
(Diabetes Mellitus, Type 2) :
In RINm5f cell membranes, the potency of AC3174 for the displacement of [ ( 125 ) I ] GLP-1 and activation of adenylate cyclase was similar to that of exenatide and GLP-1