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AKTIP — CDKN1A

Text-mined interactions from Literome

Halaschek-Wiener et al., Mol Med 2000 (Colonic Neoplasms) : Furthermore, FTS caused an upregulation of the cyclin-cyclin dependent kinase (CDK) inhibitor p21 ( waf1/cip1 ) and blocked the cell cycle
Cinghu et al., J Cell Physiol 2011 (Precancerous Conditions...) : FTS effectively represses the p21 mRNA expression in dual luciferase assay which indicates that p21 is transcriptionally regulated by this oncoprotein which in turn affect the regular cell-cycle process and its components