McLean et al., Epilepsia 2000
:
At high concentrations ( 30-600 microM ), TPM rapidly blocked SRF in about one third of the neurons tested and did not affect SRF in about one third ... In some neurons, TPM caused an intermittent limitation ( sputtering ) of SRF ( approximately 30 % of the neurons ) or blocked SRF only after a delay of several seconds ( approximately 10 % )
DeLorenzo et al., Epilepsia 2000
(Epilepsy...) :
Whole-cell current-clamp recording techniques were used to determine the effects of TPM on sustained repetitive firing (SRF) , spontaneous epileptiform-burst firing, and spontaneous recurrent seizures (SRS)
Nakamura et al., J Biol Chem 2001
:
Transcriptional activation of beta-tropomyosin mediated by serum response factor and a novel Barx homologue, Barx1b, in smooth muscle cells