Gene interactions and pathways from curated databases and text-mining

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CNR1 — IL4

Text-mined interactions from Literome

Börner et al., J Leukoc Biol 2007 : Induction of IL-4 mRNA as well as IL-4 protein release from the cells are necessary for the following induction of the CB1 gene
Börner et al., Mol Pharmacol 2008 : Interleukin-4 markedly induced transcription of CB1 in Jurkat cells and primary human T cells
Thors et al., PloS one 2010 (Prostatic Neoplasms) : Fatty acid amide hydrolase in prostate cancer : association with disease severity and outcome, CB1 receptor expression and regulation by IL-4
Kraus et al., Ann N Y Acad Sci 2012 : However, in response to the cytokine IL-4 , the epigenetic modifiers 5-aza-2'-deoxycytidine and trichostatin A, and activation of T cells, functional µ-opioid receptors and CB1 are induced