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CHUK — MAPK13

Text-mined interactions from Literome

Mizukami et al., Mol Cell Biol 2002 (MAP Kinase Signaling System) : In the interleukin-1 signaling pathway, TAK1 MAPK kinase kinase ( MAPKKK ) mediates MAPK and IKK activation via interaction with TRAF6, and TAB2 acts as an adapter linking TAK1 and TRAF6
de Alvaro et al., J Biol Chem 2004 (Insulin Resistance) : Moreover, TNF-alpha produced inhibitor kappaB kinase (IKK)-beta activation and inhibitor kappaB-beta and -alpha degradation in a p38 MAPK dependent manner, and treatment with salicylate ( an inhibitor of IKK ) completely restored insulin signaling
Lee et al., J Mol Med (Berl) 2009 : These results suggest that p38 MAPK may lead to the activation of IKK and NF-kappaB signaling, resulting in enhanced DC maturation and CXCL2 expression in response to C. difficile toxin A stimulation
Chang et al., Pharmacol Res 2009 : The YC-1 mediated increase in IKKalpha/beta activation and kappaB-luciferase activity were attenuated by GW 5074, a MAPK/ERK kinase (MEK) inhibitor ( PD 98059 ), and an ERK2 inhibitor ( AG 126 )
Slomiany et al., Inflammopharmacology 2013 : Induction in gastric mucosal prostaglandin and nitric oxide by Helicobacter pylori is dependent on MAPK/ERK mediated activation of IKK-ß and cPLA2 : modulatory effect of ghrelin
Lee et al., Proc Natl Acad Sci U S A 1998 : We have previously shown that mitogen activated protein kinase/ERK kinase kinase 1 ( MEKK1 ) can induce both this site-specific phosphorylation of IkappaB alpha at Ser-32 and Ser-36 in vivo and the activity of a high molecular weight IkappaB kinase complex in vitro