Gene interactions and pathways from curated databases and text-mining

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HGF — SELE

Text-mined interactions from Literome

Makondo et al., Biochim Biophys Acta 2004 : Hepatocyte growth factor/scatter factor suppresses TNF-alpha induced E-selectin expression in human umbilical vein endothelial cells ... Here, we tested the effect of hepatocyte growth factor (HGF) on inflammatory cytokine induced expression of E-selectin and consequent leukocyte-endothelial cell interaction using human umbilical vein endothelial cells ( HUVEC )
Gong et al., Kidney Int 2006 (Acute Disease...) : This study examined the effect of HGF on endothelial E-selectin expression in acute inflammation induced by tumor necrosis factor (TNF)-alpha ... In vitro, HGF suppressed TNF-alpha induced cell surface expression of E-selectin in human umbilical vein endothelial cells ( HUVEC ) and inhibited E-selectin mediated monocytic adhesion to endothelial monolayers
Gong et al., J Am Soc Nephrol 2006 (Chronic Disease...) : In vitro, HGF abrogated monocyte adhesion to TNF-alpha activated endothelial monolayers and suppressed endothelial expression of E-selectin , which depended on NF-kappaB signaling