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CD8A — IL10

Text-mined interactions from Literome

Tscharke et al., Arch Virol 1999 (Disease Models, Animal...) : The determine which cytokines might be involved in the CD8 ( + ) cell dependent response to ganglionic HSV infection, IL-2, IL-4, IL-6, IL-10 , and IFN-gamma mRNA levels were measured in infected ganglia from immunocompetent and anti-CD8 treated mice
Lee et al., J Interferon Cytokine Res 2000 (Mast-Cell Sarcoma) : Dose dependent and schedule dependent effects of interleukin-12 on antigen-specific CD8 responses
John et al., Infect Immun 2000 : Depletion of CD8 ( + ) cells from PBMC decreased IFN-gamma but increased IL-10 production ... CD8 ( + ) T cells are the major source of IFN-gamma but may suppress production or secretion of IL-10
Nakamura et al., J Immunol 2003 : The generation of the efferent CD8 ( + ) Tr cell in a.c. associated immune deviation is dependent on IL-10 producing, CD1d restricted, invariant Valpha14 ( + ) NKT ( iNKT ) cells
Horwitz et al., J Leukoc Biol 2003 : The role of the combination of IL-2 and TGF-beta or IL-10 in the generation and function of CD4+ CD25+ and CD8+ regulatory T cell subsets
Liu et al., J Immunol 2003 : IL-10 mediates suppression of the CD8 T cell IFN-gamma response to a novel viral epitope in a primed host
de la Barrera et al., Clin Exp Immunol 2004 (Tuberculosis, Pulmonary) : IL-10 down-regulates costimulatory molecules on Mycobacterium tuberculosis pulsed macrophages and impairs the lytic activity of CD4 and CD8 CTL in tuberculosis patients
Kang et al., J Immunol 2005 : During the primary response, the presence of IL-10 resulted in enhancement of CD8 ( + ) T cell numbers without detectable alterations in the kinetics or percentage of cells that underwent proliferation
Dercamp et al., Cancer Res 2005 (Thymoma) : Distinct and overlapping roles of interleukin-10 and CD25+ regulatory T cells in the inhibition of antitumor CD8 T-cell responses ... Here, we address some of the respective and possibly overlapping roles of IL-10 and CD25+ T ( reg ) in CD8 antitumor immunity
Cao et al., Cell Mol Immunol 2004 (Carcinoma...) : Global gene expression profiling in interleukin-12 induced activation of CD8 ( + ) cytotoxic T lymphocytes against mouse mammary Carcinoma
Willemsen et al., J Immunol 2006 (Melanoma) : The introduction of a mutated cysteine motif in CD8alpha, which prevents its binding to LCK and linker for activation of T cells, did not adversely affect expression and T cell cytotoxicity, but counteracted the CD8alpha mediated down-regulation of IL-4 and IL-5, but not IL-10
Yaddanapudi et al., FASEB J 2006 : Exposure of human and rhesus PBMC to ZEBOV, SEBOV, or MARV peptides or inactivated ZEBOV resulted in decreased expression of activation markers on CD4 and CD8 cells ; CD4 and CD8 cell apoptosis as early as 12 h postexposure ; inhibition of CD4 and CD8 cell cycle progression ; decreased interleukin (IL)-2, IFN-gamma, and IL12-p40 expression ; and increased IL-10 expression
Murugaiyan et al., J Immunol 2007 (Neoplasms) : Lower levels of CD40L expression on T cells induced IL-10 mediated suppression of tumor regressing effector CD8 ( + ) T cells and higher productions of IL-4 and IL-10
Ismail et al., Infect Immun 2007 (Disease Models, Animal...) : Depletion of IL-10 restored the number of CD4 ( + ) and CD8 ( + ) T cells in infected WT mice
Zhang et al., J Clin Invest 2007 (Influenza, Human...) : Elevated levels of IL-10 early in the response was key to the loss of CD4 ( + ) T cells, whereas CD8 ( + ) T cell deletion was dependent on a prolonged TNF-alpha response, IL-10 , and upregulation of Fas
Biswas et al., J Immunol 2007 (Listeriosis) : Pathogen-specific CD8 T cell responses are directly inhibited by IL-10 ... Herein, we demonstrate that primary and memory CD8 T cell responses following Listeria monocytogenes infection are enhanced by the absence of IL-10
Saha et al., J Immunol 2007 (Disease Susceptibility...) : Both CD4 ( + ) and CD8 ( + ) T cells were involved in IFN-gamma and IL-10 production
Björck et al., J Immunol 2008 : IC-loaded pDC stimulate CD4 ( + ) T cells to proliferate and secrete a mixture of IL-4 and IFN-gamma, and they induce CD8 ( + ) T cells to secrete IL-10 as well as IFN-gamma
Chaput et al., Gut 2009 (Adenocarcinoma...) : Finally, interleukin 6 and TGF beta 1 synergistically induced the generation of CD8 ( + ) CD25 ( + ) Foxp3 ( + ) T cells ex vivo
Parvizi et al., Vet Immunol Immunopathol 2009 (Marek Disease) : Our results indicate that cytokines could be differentially induced by MDV in CD4 ( + ) and CD8 ( + ) T cell subsets and that IL-10 may play a role in the modulation of immune response to MDV
Lee et al., J Exp Med 2009 (Lymphocytic Choriomeningitis) : Activating receptors promote NK cell expansion for maintenance, IL-10 production, and CD8 T cell regulation during viral infection
Ma et al., Scand J Immunol 2011 (Colonic Neoplasms) : This study aims to investigate the role of tumour derived Foxhead box P3 (Foxp3) ( + ) interleukin (IL)-17 ( + ) T cells on suppressing tumour-specific CD8 ( + ) T cells
Teng et al., Cancer Cell 2011 : In this issue of Cancer Cell, Mumm et al. demonstrate that pegylated IL-10 increases CD8 ( + ) T cell numbers, IFN-? secretion, and cytotoxicity in established tumors, enhancing antigen presentation machinery and suppressing tumor growth
Brisbin et al., Benef Microbes 2012 : The results demonstrated that chicken CD4+ and CD8+ T-cells express TLR21 and that the various isolates of lactobacilli differentially induces the expression of interleukin 10 , interferon-gamma and transforming growth factor beta
Das et al., J Immunol 2012 (Hepatitis B, Chronic) : Phenotypically, these cells were predominantly immature ( CD19 ( + ) CD24 ( hi ) CD38 ( hi ) ) ex vivo ; sorted CD19 ( + ) CD24 ( hi ) CD38 ( hi ) cells suppressed HBV-specific CD8 T cell responses in an IL-10 dependent manner
Höllsberg et al., Proc Natl Acad Sci U S A 1995 : CD8 T-cell stimulation with the wild-type peptide antigen led to activation of p56lck kinase activity, interleukin 2 secretion, cytotoxicity, and clonal expansion
Barth et al., Ann Surg Oncol 1996 (Sarcoma, Experimental) : In an in vitro assay, IL-10 did not inhibit CD8 lymphocyte secretion of IFN-gamma in response to tumor stimulation
Deckert-Schlüter et al., J Neuroimmunol 1997 (Chronic Disease...) : In Toxoplasma encephalitis ( TE ), CD4+ and CD8+ T-cells also contributed to the upregulated IL-10 production