Gene interactions and pathways from curated databases and text-mining

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CAV3 — TNF

Text-mined interactions from Literome

Sun et al., Eur Biophys J 2002 : As a comparison, tumor necrosis factor-a induced a decrease of caveolin-1 in the cells
Sun et al., Biorheology 2003 (Mechanotransduction, Cellular) : In contrast, TNF-alpha induced a decrease of caveolin-1 in cells
Fawzi-Grancher et al., Clin Hemorheol Microcirc 2005 : Role of Ca2+ in the effects of shear stress and TNF-alpha on caveolin-1 expression ... In contrast, TNF-alpha induced a decrease of caveolin-1 in the cells, whatever the [ Ca2+ ] i
Wang et al., Am J Respir Cell Mol Biol 2006 (Inflammation) : Loss-of-function experiments using small interfering RNA showed that down regulating caveolin-1 expression in murine alveolar and peritoneal macrophages increased LPS induced proinflammatory cytokine TNF-alpha and IL-6 production but decreased anti-inflammatory cytokine IL-10 production
Fakhrzadeh et al., Toxicol Appl Pharmacol 2008 (Pneumonia) : Regulation of caveolin-1 expression, nitric oxide production and tissue injury by tumor necrosis factor-alpha following ozone inhalation ... These data, together with our findings that TNFalpha suppressed caveolin-1 expression in cultured AM, suggest that TNFalpha and downstream signaling mediate activation of NF-kappaB and the regulation of inflammatory genes important in ozone toxicity, and that this process is linked to caveolin-1
Shao et al., PloS one 2013 : Rac1 inhibitors significantly abolished this barrier-protective effect induced by down-regulation of caveolin-1 in response to TNF-a in RPMVECs