Gene interactions and pathways from curated databases and text-mining

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CNTN2 — TXN

Text-mined interactions from Literome

Sasada et al., Mol Immunol 2002 (HTLV-I Infections) : Induction of HTLV-I Tax protein increased the expression of TRX protein in a Tax transfected Jurkat cell line, JPX-9 ... Moreover, chloramphenicol acetyltransferase (CAT) analysis with a reporter gene containing the TRX promoter revealed that Tax activates the transcription of TRX gene ... Taken together, these findings suggest that overexpressed TRX , which is induced by HTLV-I Tax , may play an important role in HTLV-I infection through the negative regulation of viral gene expression
Chowdhury et al., J Gen Virol 2003 : Both HTLV-I Tax and the proteasome-specific inhibitor MG132 inhibited p53 mediated TRX protein degradation