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CNTN2 — TXN
Text-mined interactions from Literome
Sasada et al., Mol Immunol 2002
(HTLV-I Infections) :
Induction of HTLV-I
Tax protein
increased the expression of
TRX protein in a Tax transfected Jurkat cell line, JPX-9 ... Moreover, chloramphenicol acetyltransferase (CAT) analysis with a reporter gene containing the TRX promoter revealed that
Tax activates the transcription of
TRX gene ... Taken together, these findings suggest that overexpressed
TRX , which is
induced by HTLV-I
Tax , may play an important role in HTLV-I infection through the negative regulation of viral gene expression
Chowdhury et al., J Gen Virol 2003
:
Both HTLV-I
Tax and the proteasome-specific inhibitor MG132
inhibited p53 mediated
TRX protein degradation