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APLN — MAPK3

Text-mined interactions from Literome

O'Donnell et al., J Neurochem 2007 : We found that ( i ) both APJ and apelin are expressed in hippocampal neurons ; ( ii ) apelin peptides induce phosphorylation of the cell survival kinases AKT and Raf/ERK-1/2 in hippocampal neurons ; and ( iii ) apelin peptides protect hippocampal neurons against NMDA receptor mediated excitotoxicity, including that induced by human immunodeficiency virus type 1
Bai et al., Acta Biochim Biophys Sin (Shanghai) 2008 : Apelin-13 induces ERK1/2 but not p38 MAPK activation through coupling of the human apelin receptor to the Gi2 pathway
Zeng et al., Peptides 2009 (Myocardial Reperfusion Injury) : Furthermore, apelin enhanced superoxide dismutase activity and phosphorylation of extracellular signal regulated kinase 1/2 and Akt after hypoxia/re-oxygenation