Legube et al., J Biol Chem 2004
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Moreover, Tip60 is required for p53 to activate the endogenous p21 promoter, suggesting that it functions as a p53 co-activator
Lee et al., Cell Death Differ 2013
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Together, these observations demonstrate that Tip60 mediated p21 acetylation is a novel and essential regulatory process required for p21 dependent DNA damage induced cell-cycle arrest