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BCL2 — EGF

Text-mined interactions from Literome

Ho et al., Placenta 1999 : The role of Bcl-2 expression in EGF inhibition of TNF-alpha/IFN-gamma induced villous trophoblast apoptosis
Real et al., Oncogene 2002 (Brain Neoplasms...) : In the brain subline, both expression of Bcl-2 and Stat3 activation were induced by epidermal growth factor and abrogated after treatment with kinase inhibitors specific for epidermal growth factor receptor or Jak2
Cui et al., Mol Reprod Dev 2003 : Furthermore, semi-quantitative reverse transcriptase-polymerase chain reaction ( RT-PCR ) revealed that EGF enhanced the mRNA expression of Bcl-xL in the presence of 0.4 % BSA but BSA and EGF alone had no effect ... These results suggest that EGF and BSA synergistically enhance Bcl-xL gene expression, which may result in a net increase in cell number in porcine presumptive diploid parthenotes developing in vitro
Jin et al., J Cell Physiol 2007 : Epidermal growth factor (EGF) induces Bad phosphorylation at Ser112 via mitogen activated protein kinase ( MAPK ), impairing its binding to Bcl-2 and Bcl-xL and interfering with their anti-apoptotic functions
Neiva et al., Neoplasia (New York, N.Y.) 2009 (Carcinoma, Squamous Cell) : Here, we observed that Bcl-2 signaling induces expression of IL-6, CXCL8, and EGF , providing a mechanism for the upregulation of these cytokines in tumor associated endothelial cells