Gene interactions and pathways from curated databases and text-mining

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EP300 — STAT5B

Pathways - manually collected, often from reviews:

  • BioCarta il-7 signal transduction: Nmi/p300/CBP complex (NMI-EP300-CREBBP) → STAT5/STAT5/Nmi/p300/CBP complex (STAT5A_STAT5B-NMI-EP300-CREBBP) (modification, collaborate)
  • BioCarta il-7 signal transduction: Nmi/p300/CBP complex (NMI-EP300-CREBBP) → STAT5/STAT5 complex (STAT5A_STAT5B) (modification, collaborate)
  • BioCarta il-7 signal transduction: STAT5/STAT5/Nmi/p300/CBP complex (STAT5A_STAT5B-NMI-EP300-CREBBP) → STAT5/STAT5 complex (STAT5A_STAT5B) (modification, collaborate)
  • KEGG Jak-STAT signaling pathway: CREBBP/EP300 → STAT1/STAT2/STAT3/STAT4/STAT5A/STAT5B/STAT6 (protein-protein, binding/association)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *