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HPD — IL10

Text-mined interactions from Literome

Hirsch et al., J Infect Dis 1999 (HIV Infections...) : In longitudinal studies, PPD stimulated production of IL-10 and TGF-beta returned to baseline by 3 months, whereas IFN-gamma production remained depressed for at least 12 months
Stylianou et al., APMIS 2000 (HIV Infections) : Our findings are : ( i ) After initiating HAART there were no significant changes in PHA- or MAC-PPD stimulated IL-10 and IL-12 levels in PBMC supernatants in the patient group as a whole
Mochida-Nishimura et al., Cell Immunol 2001 : M-Mphis, but not GM-Mphis, released IL-10 not only in the course of macrophage differentiation but also in response to PPD after maturation to macrophages
Elliott et al., Trans R Soc Trop Med Hyg 2004 (Disease Progression...) : For tuberculin skin test positive participants, high incidence was also associated with an IL-10 response to PPD ( adjusted RR 6.24, P = 0.03 ) ; for those with a BCG scar, high incidence was associated with positive IL-5 responses ( adjusted RRs : PPD 3.64, P = 0.006 ; CFP 3.44, P = 0.04 )
Nabeshima et al., J Infect Chemother 2005 (Tuberculosis) : The mean IL-10 production in response to PPD reached a peak at week 2, and then declined to its lowest point at week 8
Winkler et al., Microbes Infect 2005 (Tuberculosis, Pulmonary) : PPD was a weak inducer of IL-10 in T cells and insufficient in promoting cytokine production in TCRgammadelta+CD3+ cells
Moormann et al., J Infect Dis 2007 (Burkitt Lymphoma...) : IL-10 responses to EBV lytic antigens, PPD , and PHA correlated inversely with malaria exposure regardless of age
Wagner et al., Med Microbiol Immunol 2013 : PPD and LPS significantly increased IL-6, IL-10 , and TNF-a production in PBMCs. IL-10 and TNF-a production were significantly lower in a subgroup of CD patients ( 5/12 ) with a known NOD2 mutation
King et al., J Immunol 1996 (Chronic Disease...) : PPD relative to SWAP induced fivefold less IL-10 release by CD4+ cells ( p < 0.01 )