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SHH — SOX14
Text-mined interactions from Literome
Hargrave et al., Dev Biol 2000
:
The HMG box transcription factor gene
Sox14 marks a novel subset of ventral interneurons and is
regulated by
sonic hedgehog
Popovic et al., Biochim Biophys Acta 2010
:
Further, we have shown that human
SOX14 expression is GLI1 dependent in U87MG cells and
SHH-N dependent in U87MG and HepG2 cell lines ... By applying siRNA silencing of FOXA2, we have demonstrated that
upregulation of endogenous
SOX14 gene expression by
SHH is, at least in part, mediated by FOXA2 ... However, our data revealed that a positive regulatory region, containing functional FOXA2 site analyzed in this study, is not involved in mediation of
SHH dependent
SOX14 activation